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The objective of this study is to present the validation of a recently developed extension of a fuzzy quantification subsethood based algorithm on three sets of newly available breast cancer data. Results show that our algorithm is able to reproduce the seven biological classes previously identified, preserving their characterisation in terms of marker distributions and therefore their clinical meaning. Moreover, because our algorithm constitutes the fundamental basis of the newly developed Nottingham Prognostic Index Plus (NPI+), our findings demonstrate that this new medical decision making tool can help moving towards a more tailored care in breast cancer..

A fixed number of reserve crew are available for scheduling and each requires a daily standby duty start time. This work proposes a mixed integer programming approach to scheduling the airline TMs reserve crew. A simulation of the airline TMs operations with stochastic journey time and crew absence inputs (without reserve crew) is used to generate input disruption scenarios for the mixed integer programming simulation scenario model (MIPSSM) formulation.

Seth Troxler Michael Mayer: The Peacock Society (Paris, October 7): As often as not, the worst aspect of the b2b is the way certain DJs might as well just be playing self contained fifteen minute mini sets, one after the other, rather than traveling the same road. But there’s a clear mesh going on at this Paris club between Troxler, the young Detroit to Berlin transplant who’s been in the top ten of Resident Advisor’s annual DJ poll for six years running, and Mayer, the public face of Cologne’s legendary Kompakt label. Both have a taste for tangy hooks balancing freaky minimalism, and wide open, disco flavored grooves, not to mention curious vault picks, such as Emmanuel Top’s acid monster remix, from 1997, of the Age of Love’s self titled 1990 single.

Skateboarder Tony Hawk asked for, and received, permission to drive in the race’s North American portion. “He said it was fun,” Mr. Rasmussen noted. I was really not myself during the end of October and throughout November. I completely lost my fucking mind. Everything was just getting to be too much, and I couldn’t handle any of it.

Climate change activists have this clip on repeat, ready to fire off anytime a Republican denies climate change exists and/or is man made. “You know what this?” asks Sen. Jim Inhofe (R Okla.) in February 2015, holding up a tightly packed snowball fresh from a recent, late season storm.

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